Please update OpenOCD
On which OS ?
What do you mean by running your program ?
Are you using the menu Target => Program chip... ?
Or the Debug isn’t programming your appli code ?
Can you add -d in openocd options in debugger tab in debug configuration and attach the result log file ?
The previous version was working fine on the L100C disco ?
On which plugin version are you now ?
Can you try a fresh SW4STM32 install ? Installer exe have been updated.
Rgds,
Laurent